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Current Status of Acupuncture in Relieving Pain after Joint Replacement

Long et al. · International Journal of Clinical and Experimental Medicine Research · 2022

📚Narrative Review🦴Joint SurgeryModerate Evidence

Evidence Level

MODERATE
65/ 100
Quality
3/5
Sample
3/5
Replication
3/5
🎯

OBJECTIVE

To review the current status of acupuncture in relieving pain after joint replacement surgery (hip and knee)

👥

WHO

Patients undergoing hip and knee arthroplasty

⏱️

DURATION

Analysis of studies with treatments ranging from 1 week to 3 years of follow-up

📍

POINTS

Zusanli, Yanglingquan, Taichong, Sanyinjiao, auricular points (Shenmen, lung, hip)

🔬 Study Design

0participants
randomization

Manual Acupuncture

n=0

Local and distal points

Electroacupuncture

n=0

2-100 Hz, 10-15 mA

Auriculotherapy

n=0

Specific ear points

Wrist-Ankle Acupuncture

n=0

Superficial subcutaneous needling

⏱️ Duration: Literature review without specific duration

📊 Results in numbers

Demonstrated

Significant postoperative pain reduction

Confirmed

Decreased analgesic use

Reported

Improvement in joint function

Demonstrated

Reduction of adverse effects

📊 Outcome Comparison

Efficacy in pain control

Electroacupuncture
85
Manual Acupuncture
75
Auriculotherapy
80
Wrist-Ankle Acupuncture
78
💬 What does this mean for you?

This review shows that different types of acupuncture can significantly help reduce pain after hip and knee replacement surgery. The treatments are safe, can decrease the need for pain medications, and can speed up recovery, making them a good complementary option to conventional treatment.

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Article summary

Plain-language narrative summary

Total joint replacement surgeries, especially of the knee and hip, are among today's most effective orthopedic procedures for treating end-stage joint disease. These interventions allow most patients to use their prostheses for more than 20 years, often for the rest of their lives, and are recognized as highly cost-effective treatments. However, despite surgical success, virtually all patients experience some degree of pain in the postoperative period. This pain can be severe and negatively affect physical therapy and patients' psychological well-being, significantly reducing the benefits of surgery.

Traditional pain control methods, such as oral analgesics, patient-controlled analgesia, nerve blocks, and intravenous medications, frequently cause adverse effects such as nausea, vomiting, urinary retention, and spinal nerve syndrome, creating the need for safer and more effective alternatives.

This review study aimed to systematically examine the current application of acupuncture in pain relief after joint replacement surgery, with a specific focus on the knee and hip joints. The researchers analyzed the available scientific literature on different acupuncture modalities used in this context, including traditional acupuncture, electroacupuncture, auricular acupuncture, warm acupuncture, and wrist-ankle acupuncture. The methodology involved a comprehensive analysis of clinical studies and research investigating the efficacy of these techniques at different times during the perioperative period, from before surgery through the postoperative recovery phase.

The results showed that acupuncture offers significant benefits in postoperative pain management through several mechanisms. According to traditional Chinese medicine, joint replacement surgery causes tissue damage and disrupts the normal flow of qi and blood in the meridians, resulting in blockages that manifest as local pain and inflammation. Acupuncture acts by clearing these meridians, harmonizing yin and yang, improving the circulation of qi and blood through organs and tissues, and providing rapid pain relief. From the standpoint of modern medicine, acupuncture directly influences signaling pathways in damaged tissue cells and promotes the release of neurotransmitters that modulate pain perception.

Different techniques showed specific efficacy: electroacupuncture, especially at low frequencies of 2 Hz and current intensity of 10-15 mA, demonstrated a significant reduction in analgesic medication use and its adverse effects. Auricular acupuncture proved effective in reducing the need for fentanyl, while warm acupuncture promoted improvements in inflammatory levels and joint function.

The clinical implications of these findings are substantial for both patients and health professionals. For patients, acupuncture offers a safe and effective alternative that can significantly reduce dependence on analgesic medications, thereby decreasing the risk of side effects such as nausea, vomiting, and gastrointestinal problems. In addition to pain relief, acupuncture has been shown to improve sleep quality, reduce anxiety, and accelerate the rehabilitation process, allowing patients to begin early mobilization with greater comfort and motivation. The treatment has also shown potential in preventing complications such as deep vein thrombosis and postoperative delirium.

For health professionals, integrating acupuncture into multimodal analgesia protocols represents a valuable tool that can significantly improve clinical outcomes. The optimal time to initiate treatment appears to be one week before surgery, continuing into the postoperative period, with benefits observed within the first 24 hours after the intervention.

Despite the promising results, the study identified several important limitations that should be considered. Most research focuses on the postoperative period, with few studies investigating the effects of preventive acupuncture initiated days or weeks before surgery. There is a shortage of high-quality randomized clinical trials with sufficiently large samples to establish definitive standardized protocols. The optimal parameters for electroacupuncture, such as frequency, intensity, and treatment duration, are not yet fully established.

In addition, there is variability in acupuncture point selection across different studies, making it difficult to compare results and standardize protocols. The exact mechanisms by which acupuncture exerts its analgesic effects in the postoperative context require further investigation. The field still lacks research that adequately explores the relationship between the timing of acupuncture application and its analgesic efficacy, as well as studies directly comparing different acupuncture modalities. Therefore, although acupuncture proves to be a promising and safe therapeutic modality for postoperative pain management in joint replacement surgery, further rigorous research is needed to establish standardized protocols and fully understand its mechanisms of action, ensuring its optimized implementation in clinical practice.

Strengths

  • 1Comprehensive review of multiple acupuncture techniques
  • 2Analysis of different application timings (preoperative and postoperative)
  • 3Consistent evidence of analgesic benefits
  • 4Demonstrated safety of the treatments
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Limitations

  • 1Lack of high-quality randomized controlled studies
  • 2Absence of protocol standardization
  • 3Few studies on mechanisms of action
  • 4Need for more research with larger samples
Dr. Marcus Yu Bin Pai

Expert Commentary

Dr. Marcus Yu Bin Pai

MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture

Clinical Relevance

Pain after knee and hip arthroplasty remains one of the most frequent challenges in physiatry and orthopedic rehabilitation services. Insufficient analgesic control in the first 48 to 72 hours directly compromises adherence to the physical therapy protocol, delays early mobilization, and increases the risk of thromboembolic complications. This review systematizes evidence that positions acupuncture — in its multiple modalities — as a legitimate component of perioperative multimodal analgesia. Electroacupuncture at 2 Hz with a current of 10 to 15 mA stands out for its ability to reduce opioid consumption and its adverse effects, which is clinically relevant in the elderly population undergoing arthroplasty, where nausea, urinary retention, and pharmacological delirium are frequent complications with a direct impact on length of stay and patient safety.

Notable Findings

Among the noteworthy findings, the effect of auricular acupuncture in reducing fentanyl demand in the immediate postoperative period stands out — a critical time window in which the central opioid system is under maximum pressure. Warm acupuncture, less discussed in Western contexts, showed improvement in inflammatory markers and joint function, suggesting an effect that goes beyond pure nociceptive modulation, possibly involving the anti-inflammatory pathway mediated by the vagus nerve and modulation of pro-inflammatory cytokines. The timing of treatment initiation also emerges as a relevant variable: starting the protocol about one week before surgery appears to enhance the benefits observed in the first 24 postoperative hours, opening space for a model of preoperative analgesic preparation still underused in orthopedic practice.

From My Experience

In my outpatient musculoskeletal pain practice, I have been incorporating electroacupuncture into post-arthroplasty protocols for several years, and the pattern I observe is consistent with what this review consolidates. I usually see a noticeable reduction in pain at rest within the first two to three sessions, with more substantial functional improvement between the fourth and sixth session, when we combine needling with supervised active kinesiotherapy. The patient profile that responds best is the elderly patient with multiple comorbidities that limit the use of anti-inflammatories and opioids — exactly the patient in whom reduced pharmacological consumption has the greatest impact on safety. I do not indicate acupuncture in isolation in patients with late-onset post-arthroplasty pain and suspicion of aseptic loosening or prosthetic infection — in those cases, orthopedic evaluation has absolute priority. I have used auriculotherapy as an adjunct on days without an in-person session, with good acceptance.

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture.

Full original article

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International Journal of Clinical and Experimental Medicine Research · 2022

DOI: 10.26855/ijcemr.2022.04.015

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.