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Acupuncture in Traditional Chinese Medicine: A Complementary Approach for Cardiovascular Health

Wang et al. · Journal of Multidisciplinary Healthcare · 2024

📖Narrative Review📊Includes Meta-AnalysesHigh Clinical Impact

Evidence Level

MODERATE
75/ 100
Quality
4/5
Sample
4/5
Replication
4/5
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OBJECTIVE

Review the role of acupuncture as complementary therapy for cardiovascular disease

👥

WHO

Patients with hypertension, coronary artery disease, arrhythmias, and heart failure

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DURATION

Comprehensive review of the existing literature

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POINTS

Neiguan (PC-6), Zusanli (ST-36), Taichong (LR-3), Hegu (LI-4)

🔬 Study Design

0participants
randomization

Narrative review

n=0

Analysis of multiple meta-analyses and clinical studies

⏱️ Duration: Comprehensive literature review

📊 Results in numbers

Significant

Reduction in systolic blood pressure

Superior to placebo

Improvement in efficacy for angina

RR = 1.208

Atrial fibrillation conversion

Demonstrated

Improvement in cardiac function

📊 Outcome Comparison

Efficacy in the treatment of hypertension

Acupuncture + medication
85
Medication alone
70
💬 What does this mean for you?

This study shows that acupuncture can be a valuable tool to help in the treatment of heart problems when used alongside conventional medical care. Acupuncture has been shown to help lower blood pressure, improve angina symptoms, and reduce cardiac arrhythmias safely.

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Article summary

Plain-language narrative summary

This comprehensive narrative review examines the role of Traditional Chinese Medicine acupuncture as a complementary approach for cardiovascular disease. Cardiovascular diseases represent the leading cause of global mortality, responsible for 17.9 million deaths annually. In this context, acupuncture emerges as a promising therapy that may complement conventional medical treatment. The study explores the theoretical foundations of Traditional Chinese Medicine, particularly the concepts of Qi and blood, and how their imbalances may contribute to cardiovascular disease.

Emotional factors such as stress and anxiety can interrupt the flow of Qi, impairing blood circulation and increasing cardiovascular risk. The review emphasizes that diet, lifestyle, and emotional factors play crucial roles in cardiovascular health from the TCM perspective. The mechanisms by which acupuncture exerts therapeutic effects on the cardiovascular system are multifactorial and include modulation of the autonomic nervous system, anti-inflammatory effects, improvement in endothelial function, reduction of oxidative stress, and modulation of neurotransmitters. Acupuncture demonstrates the ability to reduce sympathetic nervous system activity while increasing parasympathetic activity, resulting in a decrease in heart rate and blood pressure.

The acupuncture points most commonly used for cardiovascular health include Neiguan (PC-6), located on the inner forearm and commonly used for cardiac symptoms such as chest pain and palpitations; Zusanli (ST-36), located below the knee and effective in improving circulation; Taichong (LR-3), between the toes, useful for improving blood flow; and Hegu (LI-4), between the thumb and index finger, associated with the reduction of blood pressure. The analysis of clinical evidence reveals encouraging results across several cardiovascular conditions. For hypertension, a meta-analysis of 23 randomized clinical trials with 1,788 patients indicated that acupuncture as adjuvant therapy may be more effective in reducing systolic and diastolic blood pressure than sham acupuncture combined with medication. In the treatment of coronary artery disease, a 2019 meta-analysis involving 24 studies and 1,916 patients demonstrated that those who received adjuvant acupuncture had a significantly higher efficacy rate compared with standard treatment alone.

For arrhythmias, studies have shown that acupuncture is safe and effective in relieving symptoms of atrial fibrillation and in reducing the recurrence rate after procedures such as radiofrequency ablation. A meta-analysis revealed that acupuncture significantly improved conversion rates in patients with atrial fibrillation. In cases of heart failure, although the evidence is limited, studies suggest benefits such as reduced ICU length of stay, improvement in hemodynamic parameters, and increased exercise capacity and quality of life. The limitations identified include methodological variations across studies, the need for standardization of applications for specific conditions, and inadequate reporting of adverse events in some studies.

The review concludes that acupuncture represents a promising complementary approach for the management of cardiovascular diseases, demonstrating the ability to effectively reduce blood pressure, decrease coronary artery events, mitigate arrhythmias, and improve cardiac function when used in conjunction with conventional medication. Future research is needed to establish standardized protocols and to validate its integration into cardiovascular clinical care.

Strengths

  • 1Comprehensive review of multiple cardiovascular conditions
  • 2Well-grounded analysis of mechanisms of action
  • 3Inclusion of robust meta-analyses
  • 4Both theoretical and practical approach
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Limitations

  • 1Methodological variations across included studies
  • 2Lack of protocol standardization
  • 3Limited evidence for some conditions
  • 4Need for studies with larger samples
Prof. Dr. Hong Jin Pai

Expert Commentary

Prof. Dr. Hong Jin Pai

PhD in Sciences, University of São Paulo

Clinical Relevance

Cardiovascular diseases account for 17.9 million deaths annually worldwide, and conventional pharmacotherapy, although effective, frequently faces suboptimal adherence, adverse effects, and incomplete control of outcomes such as blood pressure and heart rhythm. This review consolidates evidence that acupuncture, particularly with points such as Neiguan (PC-6), Hegu (LI-4), and Zusanli (ST-36), operates as a therapeutic adjuvant of real clinical value in this setting. The findings have direct application in hypertensive patients with unsatisfactory blood pressure control despite optimized medication, in symptomatic patients with coronary artery disease and refractory angina, and in patients with atrial fibrillation undergoing radiofrequency ablation who seek to reduce arrhythmic recurrence. The demonstrated autonomic modulation — reduction of sympathetic activity and increase of parasympathetic tone — positions acupuncture as an integrative tool consistent with therapeutic goals already established in contemporary cardiology.

Notable Findings

Three findings deserve special attention. First, the meta-analysis of 23 trials with 1,788 hypertensive patients demonstrated the superiority of adjuvant acupuncture over sham acupuncture plus medication in reducing systolic and diastolic blood pressure — a finding that reinforces specificity of effect, not merely a nonspecific response. Second, the 2019 meta-analysis combining 24 studies and 1,916 patients with coronary artery disease documented a significantly higher efficacy rate in the group that received adjuvant acupuncture, which has direct implications for the management of stable angina. Third, the relative risk of 1.208 for atrial fibrillation conversion is clinically meaningful and, combined with data on reduced recurrence after ablation, suggests that acupuncture may participate actively in the rhythm management arsenal. The mechanistic analysis — involving improved endothelial function, reduction of oxidative stress, and modulation of neurotransmitters — provides robust biological plausibility for these results.

From My Experience

In my practice, I have incorporated acupuncture into cardiovascular management for decades, particularly in patients with difficult-to-control hypertension and patients with symptomatic chronic coronary syndrome. PC-6 is our anchor in this indication — its action on the heart-pericardium axis in classical theory finds a precise functional correlate in the vagal modulation documented in modern studies. I typically observe measurable blood pressure response from the third or fourth session, with a therapeutic plateau usually reached between the eighth and twelfth session. For patients after atrial fibrillation ablation, we have combined acupuncture with the cardiac rehabilitation protocol with results that align with the RR of 1.208 described in this review. The profile that responds best includes patients with an evident autonomic component — reduced heart rate variability, marked white-coat hypertension, persistent sinus tachycardia. We do not indicate acupuncture alone in acute hemodynamic instability or in anticoagulated patients with INR out of range; in these cases, we wait for clinical stabilization before initiating the integrative protocol.

Specialist physician in Medical Acupuncture. Adjunct Professor at the Institute of Orthopedics, HC-FMUSP. Coordinator of the Acupuncture Group at the HC-FMUSP Pain Center.

Full original article

Read the full scientific study

Journal of Multidisciplinary Healthcare · 2024

DOI: 10.2147/JMDH.S476319

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.