Effect of acupuncture treatment on chronic neck and shoulder pain in sedentary female workers: a 6-month and 3-year follow-up study

He et al. · Pain · 2004

🎯Controlled RCT👥n = 24High Impact

Evidence Level

MODERATE
78/ 100
Quality
4/5
Sample
2/5
Replication
4/5
🎯

OBJECTIVE

To investigate whether acupuncture reduces chronic neck and shoulder pain in sedentary female workers and whether the effects are durable

👥

WHO

24 female office workers (47 ± 9 years) with pain for 12 ± 9 years

⏱️

DURATION

10 sessions over 3–4 weeks with 3-year follow-up

📍

POINTS

16 body points (GB-21, BL-12, GV-14, LI-4, LI-11) plus 6 auricular points with electroacupuncture

🔬 Study Design

24participants
randomization

Real acupuncture

n=14

Therapeutic points + electroacupuncture + auricular acupressure

Placebo acupuncture

n=10

Sham points without electrical stimulation + placebo auricular acupressure

⏱️ Duration: 10 treatments over 3–4 weeks

📊 Results in numbers

0%

Pain intensity reduction (real group)

0%

Pain intensity reduction (placebo group)

p < 0.001

Headache improvement at 3 years

64 ± 13 kPa

Increase in pain threshold at the trapezius

Percentage highlights

74%
Pain intensity reduction (real group)
25%
Pain intensity reduction (placebo group)

📊 Outcome Comparison

Pain intensity (0–100)

Real acupuncture
15
Placebo
36

Pain frequency at 3 years

Real acupuncture
19
Placebo
46
💬 What does this mean for you?

This study showed that real acupuncture was far more effective than sham acupuncture for reducing chronic neck and shoulder pain. Most impressively, the benefits lasted for 3 years after treatment, offering real hope for those who suffer with these work-related pains.

📝

Article summary

Plain-language narrative summary

The article in question investigated the effects of acupuncture in the treatment of chronic neck and shoulder pain in sedentary female workers, with long-term follow-up. This is a question of great medical and social relevance, since chronic pain in these regions is one of the leading occupational health problems. According to data presented in the study, in Norway about 13% of the working population reports moderate or severe neck and shoulder pain, and 11% of women on long-term sick leave suffer from this type of pain. The socioeconomic cost of this absenteeism is considerable, making the search for effective treatments fundamental.

Neck and shoulder pain is among the leading reasons patients seek acupuncture treatment, and 19% of patients seen in general medical practices who seek acupuncture suffer from these problems.

The primary aim of the study was to examine whether acupuncture treatment could reduce chronic neck and shoulder pain, as well as related headaches, and to verify whether any effects would be durable. To this end, the researchers conducted a randomized, controlled clinical trial with 24 female office workers, with a mean age of 47 years, who had had neck and shoulder pain for approximately 12 years. Participants were randomly divided into two groups: a test group that received real acupuncture at points considered effective for pain, and a control group that received placebo acupuncture at sham points. Treatment consisted of 10 sessions delivered over 3 to 4 weeks, combining body acupuncture, electroacupuncture, and auricular acupressure.

To assess outcomes, the researchers used questionnaires on pain and headache intensity and frequency, as well as objective measurements of the pain threshold at 28 trigger points using a device called an algometer. Assessments were performed before the first treatment, after the last treatment, six months later, and three years after the end of treatment.

The results clearly demonstrated the efficacy of real acupuncture compared with placebo. Pain intensity and frequency decreased significantly more in the group that received real acupuncture than in the placebo group during the treatment period. Specifically, pain intensity in the treated group fell to about 26% of the initial value, while in the placebo group it remained at 75% of the original value. The degree of headache also decreased more sharply in the treated group, falling to 30% of the pre-treatment value.

Algometer measurements showed that several muscles in the treated group exhibited an increased pain threshold, indicating less sensitivity and muscle pain. Particularly notable was the finding that these benefits persisted for an extraordinarily long period: three years after the end of treatment, the group that received real acupuncture still reported less pain than before treatment, while the placebo group had returned to baseline pain levels.

The clinical implications of this study are substantial for both patients and health professionals. For patients suffering from chronic neck and shoulder pain, the results offer hope of durable relief through a non-pharmacologic treatment with minimal side effects. The fact that the benefits persisted for three years is particularly encouraging, since many treatments for chronic pain offer only temporary relief. For health professionals, the study provides robust evidence that acupuncture can be a valuable therapeutic option, especially considering that the treatment regimen was relatively intensive but limited in time — only 10 sessions over a month.

The study also suggests that at least 8 to 10 sessions are required to achieve significant results, important information for treatment planning. Furthermore, the combination of different acupuncture techniques (body, electroacupuncture, and auricular acupressure) appears to have contributed to the efficacy of treatment.

Despite the promising results, the study has some important limitations that should be considered. The sample size was relatively small, with only 24 participants, which may limit generalization of the results. In addition, the study was conducted exclusively with female office workers, so the results may not apply to men or to people in other types of occupation. The acupuncturist was not blinded to the type of treatment administered, which could introduce some bias, although the physician who performed the assessments did not know which group each patient belonged to.

Another consideration is that during the three-year follow-up period, some participants received other treatments, although the authors believe this did not significantly influence the results given the occasional nature of those treatments. Finally, it is important to note that the study was carried out in Norway with a specific group of female workers, and different populations or health systems may show different results. Despite these limitations, this study represents a valuable contribution to the scientific literature on acupuncture, especially because of its unprecedented long-term follow-up, providing convincing evidence that acupuncture can offer durable relief for chronic neck and shoulder pain.

Strengths

  • 1Long-term follow-up (3 years) — rare in the literature
  • 2Objective assessment with algometry in addition to questionnaires
  • 3Well-structured control group with placebo acupuncture
  • 4Homogeneous population of female workers with similar characteristics
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Limitations

  • 1Small sample (only 24 participants)
  • 2Female office workers only
  • 3Acupuncturist was not blinded to treatment
  • 4Lack of cost-effectiveness analysis
Dr. Marcus Yu Bin Pai

Expert Commentary

Dr. Marcus Yu Bin Pai

MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture

Clinical Relevance

Occupational neck and shoulder pain is one of the most prevalent conditions in physiatry and occupational medicine clinics, and the major clinical challenge is not obtaining immediate relief — it is sustaining it. He et al.'s work addresses precisely this bottleneck by demonstrating that a 10-session cycle combining body acupuncture, electroacupuncture, and auricular acupressure produced a 74% reduction in pain intensity in workers with long-standing chronic pain, with the benefit verified to persist over three years. From a practical standpoint, this positions acupuncture as a structuring intervention — not merely palliative — in the management of occupational neck pain. The protocol is particularly applicable to female patients in sedentary work who do not tolerate long-term anti-inflammatories or who have already exhausted satisfactory responses to conventional physiotherapy in isolation.

Notable Findings

The most clinically expressive finding is not the immediate pain reduction — it is the durability of the effect at three years, in a context in which the placebo group returned to baseline pain levels over that same interval. This divergence in the trajectories of the two groups over time suggests that real acupuncture induced a sustained modification in nociceptive processing mechanisms, and not merely transient analgesia from a non-specific effect. Reinforcing this hypothesis is the increase in pain threshold on algometry at the trapezius — 64 ± 13 kPa — evidencing a measurable change in peripheral and possibly central sensitization. The significant improvement in headache (p < 0.001) at the three-year follow-up is a relevant collateral finding, since tension headache of cervicogenic origin is a frequent complaint in this population and is rarely treated in a targeted manner. The combination of subjective and objective outcomes lends differentiated interpretive weight to the body of results.

From My Experience

In my practice at the Pain Center, female office workers with chronic neck pain are one of the profiles that respond best to acupuncture when the picture involves moderate central sensitization and active trigger points in the upper trapezius and levator scapulae. I usually observe the first clinically perceptible responses between the third and fifth sessions — reduction in the frequency of painful episodes and improved sleep, which is invariably impaired. To consolidate the benefit, I typically work with cycles of eight to ten sessions, exactly along the lines of the protocol used in this article. The combination I have used most consistently is electroacupuncture at local and distal points associated with dry needling of active trigger points — an integration that this study, by using electroacupuncture as a central component, indirectly supports. Patients with a high occupational stress load and poor adherence to exercise tend to respond less, and in those cases I prescribe monthly maintenance sessions after the initial cycle. The profile that best responds, in my observation, is the patient with predominantly myofascial pain, without significant radicular radiation and with imaging studies showing no relevant structural compression.

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture.

Full original article

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Pain · 2004

DOI: 10.1016/j.pain.2004.01.018

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.