Acupuncture sensation during ultrasound guided acupuncture needling

Park et al. · Acupuncture in Medicine · 2011

🔬Controlled Pilot Study👥n = 5 participants🎯Proof of Concept
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OBJECTIVE

Investigate sensations experienced during ultrasound-guided needling across different tissue layers

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WHO

5 healthy volunteers (3 men, 2 women, 28-36 years old)

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DURATION

1 testing session of 1-2 hours per participant

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POINTS

LI-13 (Shouwuli) and LU-4 (Xiabai) on the arm, compared with control points

🔬 Study Design

5participants
randomization

Acupuncture Points

n=5

Needling at traditional points LI-13 and LU-4

Control Points

n=5

Needling 3 cm distant from traditional points

⏱️ Duration: 1-2 hours per participant

📊 Results in numbers

p = 0.007

Superficial sensations (pricking/sharp) in layers 1-2

p = 0.002

Deep sensations (heaviness/dull ache) in layers 3-4

p = 0.021

Rotation increases deep sensations in layer 3

p = 0.006

Difference between real and control points only at layer 4

📊 Outcome Comparison

Frequency of superficial sensations (pricking/sharp)

Layers 1-2
28
Layers 3-4
14

Frequency of deep sensations (heaviness/dull ache)

Layers 1-2
1
Layers 3-4
11
💬 What does this mean for you?

This pioneering study shows that sensations during acupuncture depend more on needle depth than on the exact site of insertion. This may explain why different acupuncture techniques (deeper Chinese vs. more superficial Japanese) produce distinct sensations, helping to refine future treatments.

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Article summary

Plain-language narrative summary

This innovative pilot study scientifically investigated one of the foundations of traditional acupuncture: the sensations experienced during treatment, known as 'de qi' (得氣). Using a revolutionary approach combining real-time ultrasound with validated sensation questionnaires, the researchers mapped, for the first time, the specific sensations associated with different anatomical depths during needling. The study enrolled five healthy volunteers who received needling at four distinct tissue levels: epidermal (skin surface), dermal (skin layer), fascial (connective tissue surrounding muscle), and intramuscular (within muscle). The researchers tested both traditional acupuncture points (LI-13 and LU-4) and control points located 3 cm distant from the classical meridians.

The methodology included two needle manipulation techniques: simple oscillation (vertical movement) and oscillation combined with rotation. The results revealed distinct, statistically significant patterns of sensation at different depths. In the more superficial layers (epidermal and dermal), sensations described as 'pricking' and 'sharp' predominated (p = 0.007), while in the deeper layers (fascial and intramuscular), sensations of 'heaviness,' 'dull ache,' and 'radiation' were more common (p = 0.002). Surprisingly, there were no significant differences between traditional acupuncture points and control points at most depths tested, except in the deepest intramuscular layer (p = 0.006).

The needle rotation technique significantly increased deep sensations in the fascial layer (p = 0.021) but did not affect superficial sensations, suggesting that needle manipulation may have specific effects depending on depth. These findings challenge traditional concepts of acupuncture point specificity and suggest that anatomical depth may be more important than the exact location of the point. The study also provides scientific evidence to explain why different acupuncture schools (Chinese with deep needling versus Japanese with superficial needling) report distinct sensations. The clinical implications are significant, as they may lead to the development of more standardized and objective treatment protocols.

The research opens the way for future studies that combine objective measures (force and torque) with subjective sensation assessments. Limitations include the small sample size, the purely subjective nature of sensation measures, and the lack of data on real clinical efficacy. Larger studies are needed to confirm these preliminary findings and to investigate whether these differences in sensation translate into different therapeutic outcomes.

Strengths

  • 1First study to combine ultrasound with sensation questionnaires
  • 2Innovative methodology based on real anatomy rather than arbitrary depths
  • 3Rigorous scientific approach to traditional concepts
  • 4Adequate randomization of sequence and laterality
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Limitations

  • 1Very small sample size (n = 5)
  • 2Purely subjective measures without objective data
  • 3Did not assess real clinical efficacy
  • 4Lack of force/torque measurements during needling
Prof. Dr. Hong Jin Pai

Expert Commentary

Prof. Dr. Hong Jin Pai

PhD in Sciences, University of São Paulo

Clinical Relevance

The question of insertion depth rarely receives the attention it deserves in clinical protocols, and this work by Park et al. offers a methodological contribution that should reorient how we prescribe and document our techniques. By demonstrating that superficial sensations—pricking, sharp—predominate in the epidermal and dermal layers (p = 0.007), while heaviness, dull ache, and radiation emerge in the fascial and intramuscular layers (p = 0.002), the study offers an anatomical language for something experienced clinicians already know intuitively but rarely formalize. This has direct application in selecting an approach for different populations: patients with central sensitization, older adults with atrophic tissue, or children may benefit from superficial needling with a more manageable sensation profile, while deep myofascial pain syndromes demand access to the fascial and intramuscular layers to produce therapeutically relevant de qi.

Notable Findings

The most thought-provoking finding is not the confirmation that depth determines the quality of sensation—that was expected—but the discovery that traditional points and control points produced statistically equivalent sensations at all depths, except in the deepest intramuscular layer (p = 0.006). This suggests that classical point specificity may emerge precisely at the deepest tissue plane, where the density of neural and fascial structures is greatest, rather than at the surface. Equally relevant is the effect of needle rotation: it selectively amplified sensations in the fascial layer (p = 0.021) without affecting superficial ones, indicating that manipulation is not a global amplifier but a modifier with tissue-specific effects. The combination of real-time ultrasound with a sensation questionnaire validates a methodological strategy that overcomes the historical limitation of arbitrary depths in research protocols.

From My Experience

In my practice at the Pain Center of HC-FMUSP, the question of needling depth is one of the first I ask when a colleague reports an unsatisfactory acupuncture result. I have consistently observed that patients with chronic myofascial pain—upper trapezius syndrome, lumbar pain with a pronounced muscular component—respond qualitatively differently when we reach the muscle fascia with confirmation of a sensation of heaviness or distension reported by the patient. I usually see the first analgesic responses from the third or fourth session onward when deep de qi is obtained, with cycles of eight to twelve sessions for moderate cases before spacing to monthly maintenance. Needle rotation to amplify fascial sensations—precisely what the study confirms at p = 0.021—is a maneuver I routinely associate with needling at LI-4, GB-34, and deep Ashi points. The patient profile that responds best to this sensation-guided approach is the adult with an excess pattern of pain, without marked central sensitization, who tolerates and clearly reports de qi.

Specialist physician in Medical Acupuncture. Adjunct Professor at the Institute of Orthopedics, HC-FMUSP. Coordinator of the Acupuncture Group at the HC-FMUSP Pain Center.

Full original article

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Acupuncture in Medicine · 2011

DOI: 10.1136/aim.2010.003616

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.