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01 · IDIOMA · LANGUAGE

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Dr. Marcus Yu Bin Pai·Physician Acupuncturist

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acupuntura.com · 2025–2026Last reviewed: 2026-05-04
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ResearchFull Analysis
December 18, 2024
6 min reading time

Jingjin Acupuncture for Peripheral Facial Palsy: Meta-Analysis of 19 Randomized Clinical Trials with 1,436 Patients

Systematic review and meta-analysis (19 RCTs, 1,436 patients) published in Frontiers in Neurology in December 2024: Jingjin acupuncture demonstrates an odds ratio of 3.93 (95% CI 2.78–5.56) for overall effectiveness and RR 1.69 (95% CI 1.51–1.90) for complete functional recovery rate compared with conventional treatment of peripheral facial palsy.

Source: Frontiers in Neurology(in English)DOI: 10.3389/fneur.2024.1459738
Jingjin Acupuncture for Peripheral Facial Palsy: Meta-Analysis of 19 Randomized Clinical Trials with 1,436 Patients

Peripheral facial palsy — which includes idiopathic Bell’s palsy and forms secondary to herpes zoster oticus (Ramsay Hunt syndrome), trauma, parotitis, and other causes — affects approximately 20–30 people per 100,000 inhabitants/year. Conventional treatment combines early systemic corticosteroid (prednisone for 10 days), antivirals when indicated (suspicion of herpetic etiology), and facial physical therapy. Even with timely treatment, up to 30% of patients develop permanent sequelae: facial asymmetry, synkinesis, lagophthalmos, or hemifacial spasm. A meta-analysis published in Frontiers in Neurology in December 2024, pooling 19 RCTs with 1,436 patients, demonstrates that Jingjin acupuncture — a systematized approach based on the muscle tendons of the meridians — offers superior results to conventional treatment alone.

The Jingjin technique (經筋, also romanized as jing jin) is based on the theory of the tendinous bands of the 12 meridians — structures that traverse the musculoskeletal systems of the body and that, in classical acupuncture medicine, are responsible for movement and facial expression. In contrast with conventional meridional acupuncture (which selects acupoints along the trajectory of the energy meridians), Jingjin focuses on direct treatment of the muscles and tendons affected by paralysis, with insertion of needles into the very paretic muscle bellies — especially the branches of the facial nerve (cranial nerve VII) that innervate the mimetic musculature. The authors searched for evidence in PubMed, EMBASE, Cochrane, SCOPUS, Web of Science, PEDro, and Chinese databases, covering studies through April 2024.

RESULTS OF JINGJIN ACUPUNCTURE META-ANALYSIS FOR FACIAL PALSY (FRONTIERS NEUROLOGY, DEC 2024)

19
RCTS INCLUDED IN THE META-ANALYSIS
PROSPERO: CRD42024543195 · through April 2024
1,436
PATIENTS WITH PERIPHERAL FACIAL PALSY
Jingjin acupuncture vs. conventional therapy
OR 3.93
ODDS RATIO FOR OVERALL EFFECTIVENESS
95% CI: 2.78–5.56 · Jingjin acupuncture vs. conventional therapy
RR 1.69
COMPLETE FUNCTIONAL RECOVERY RATE
95% CI: 1.51–1.90 · for complete clinical response (House-Brackmann I-II) vs. control
Jingjin
APPROACH BASED ON MERIDIAN TENDONS
Focuses on affected mimetic muscles directly — different from conventional meridional acupuncture
Cranial VII
FACIAL NERVE AS THERAPY TARGET
Protocol integrates electroneuromyographic evaluation to monitor recovery

What is Jingjin acupuncture and how does it differ from the conventional approach?

Conventional acupuncture for facial palsy selects classical acupoints along the meridians that traverse the face — mainly GB (Gallbladder), ST (Stomach), LI (Large Intestine), and TE (Triple Energizer) — inserting needles at the numbered acupoints. This approach has documented efficacy, but Jingjin proposes a conceptual difference: instead of needling the classical points, the medical acupuncturist inserts needles directly into the bellies of the paretic facial muscles (orbicularis oculi, zygomaticus, buccinator, orbicularis oris), stimulating reinnervation and recruitment of motor units. This approach is analogous to the neuromuscular electrical stimulation used by physical therapy, but with the additional mechanism of release of local neuropeptides and modulation of the axonal growth cone.

Outcome assessment used standardized tools: the Facial Disability Index (FDI) in physical and social subscales, the House-Brackmann (HB) scale of grade I–VI for classification of facial dysfunction, the Portmann scale for segmental muscle strength, and the facial nerve function score (FNFS). The meta-analysis demonstrated superiority of Jingjin in all of these functional outcomes, with an odds ratio of 3.93 for overall effectiveness — meaning that the probability of favorable response is almost four times greater with Jingjin acupuncture than with conventional therapy alone.

PATHOPHYSIOLOGY OF BELL’S PALSY AND ACUPUNCTURE MECHANISMS

Bell’s palsy results from inflammation and edema of the facial nerve in the Fallopian canal — a bony, inelastic canal where edema causes axonal compression. Mechanisms by which Jingjin acupuncture may reverse this process include:

  • Reduction of intraneural edema: stimulus of periauricular acupoints (TE-17, GB-12) modulates the autonomic nervous system and reduces local vascular permeability in the Fallopian canal
  • Direct stimulation of the paralyzed muscle: insertion into the muscle belly creates controlled microlesions that, in experimental studies, were associated with local increases in neurotrophic factors (BDNF, NT-3) potentially involved in axonal survival and growth
  • Prevention of disuse atrophy: mechanical stimulus and local inflammatory response maintain muscle trophism during the period of Wallerian degeneration — critical to avoid permanent sequelae
  • Immunologic modulation: in cases of herpetic etiology (HSV-1), acupuncture may modulate the local immune response — relevant since herpes simplex reactivation is implicated in 70–80% of Bell’s palsy cases
  • Reduction of synkinesis: preliminary evidence suggests that early Jingjin may reduce the incidence of aberrant reinnervation, which is the main cause of post-paralysis facial synkinesis

Results and magnitude of effect

The magnitude of effect demonstrated by the meta-analysis is notable: An OR of 3.93 for overall effectiveness suggests a substantial increase in the chance of response, although direct translation of odds ratios into absolute proportions depends on the baseline rate of the comparator. The data of RR 1.69 for complete functional recovery rate is equally striking: for every patient with clinical resolution from conventional treatment alone, the Jingjin group presents 1.69 complete recoveries — a 69% increase in the probability of complete clinical response (House-Brackmann I-II). This magnitude places Jingjin acupuncture among the adjuvant interventions with the greatest documented impact in facial palsy.

The authors acknowledge that most included studies present methodologic limitations — especially regarding blinding, which is structurally difficult in acupuncture studies with observational functional outcomes. PROSPERO was registered (CRD42024543195), and the search included international and Chinese databases, minimizing publication bias. Heterogeneity across studies was moderate to high for some outcomes, which the authors attribute to variability of the Jingjin protocols used across centers.

INSIGHT

Peripheral facial palsy is one of the conditions where I most see the difference of medical acupuncture in real practice. The patient arrives with facial asymmetry, lagophthalmos, and difficulty pronouncing words — devastating conditions for self-esteem and social life. Conventional treatment with prednisone is fundamental and should be initiated within the first 72 hours, but even with it, a portion of patients remains with sequelae. The Jingjin approach brings a different logic from the acupuncture of classical points: you are needling directly into the paralyzed muscle, stimulating its reinnervation and preventing atrophy. It is an approach that makes biomechanical sense and that this meta-analysis validates with data from 1,436 patients. For the neurologist or otolaryngologist who diagnoses Bell’s palsy, early referral to the medical acupuncturist — within the first two weeks — should be part of the protocol, not a late option of last choice.
— Dr. Marcus Yu Bin Pai · CRM-SP 158074 · RQE 65523 / 65524 / 655241

LIMITATIONS ACKNOWLEDGED BY THE AUTHORS

  • Small number of high-quality studies — the authors acknowledge that conclusions are “limited by the small number of methodologically rigorous studies”
  • Blinding structurally difficult in acupuncture studies with facial functional outcomes — impossible to blind the evaluator examining the face
  • Variability in Jingjin protocols across centers — different interpretations of the technique make standardization difficult
  • Most RCTs include patients with idiopathic Bell’s palsy — generalization to Ramsay Hunt palsy and other etiologies requires caution
  • Absence of long-term follow-up (>6 months) to evaluate recurrence and presence of late synkinesis

IMPLICATIONS FOR MEDICAL PRACTICE

  • Initiate Jingjin acupuncture as early as possible — ideally in the first week after onset of paralysis, simultaneously with corticosteroid
  • The Jingjin technique requires specific training in musculoskeletal acupuncture; the medical acupuncturist should have familiarity with facial muscle anatomy and electroacupuncture
  • Electroneuromyographic (ENMG) evaluation before and after treatment documents the evolution of reinnervation — an objective datum for follow-up and for communication with the neurologist
  • Suggested frequency: 5 weekly sessions in the first 4 weeks (acute phase of reinnervation), reducing to 3×/week with documented improvement
  • Low-frequency electroacupuncture (2–4 Hz) at affected muscles potentiates the motor-unit-recruitment effect — consider associating manual Jingjin technique with electroacupuncture
  • Instruct the patient on supervised facial exercises as a complement — acupuncture creates the reinnervation environment, but muscle activity consolidates the new motor patterns
FREQUENTLY ASKED QUESTIONS · 03

Frequently Asked Questions

Conventional acupuncture for facial palsy selects classical numbered acupoints along the facial meridians (GB-14, ST-4, ST-6, LI-20, TE-17, among others). The Jingjin approach goes further: the medical acupuncturist identifies the specific muscle bellies that are paralyzed (orbicularis oculi, zygomaticus, buccinator) and inserts needles directly into those muscles, stimulating local reinnervation through controlled microlesions and release of neurotrophic factors. In clinical practice, many medical acupuncturists combine the two approaches — classical points for systemic modulation and Jingjin muscle insertion for local stimulation.

The ideal recovery window is in the first 4–8 weeks, when the process of Wallerian degeneration and spontaneous reinnervation is still active. In the RCTs of this meta-analysis, most patients were treated in the acute-subacute phase. For cases with long-standing palsy (more than 3 months without recovery), the prospects for complete recovery are smaller, but acupuncture can still contribute to: reduction of established synkinesis, improvement of residual functionality of partially reinnervated muscles, and relief of hemifacial spasm. Individual clinical evaluation is indispensable.

Yes, for the Jingjin technique the treatment is essentially local — needles are inserted into the affected facial muscles. This may seem intimidating to the patient, but the needles used are extremely fine (0.20–0.25 mm), and the procedure is well tolerated in most cases, especially considering that the sensation of pain is already altered by facial neuropathy. In a complementary way, the medical acupuncturist uses distal acupoints in the upper and lower limbs for systemic modulation — such as LI-4 (Hegu), ST-36 (Zusanli), and GB-34 (Yanglingquan) — which potentiate the local effect without additional facial needling.

Fonte Original

Frontiers in Neurology(em inglês)

Estudo Científico

DOI: 10.3389/fneur.2024.1459738
Content prepared by
CEIMEC — Centro de Estudo Integrado de Medicina Chinesa

Founded in 1989 by physicians trained at the University of São Paulo (USP) and specialized in China, CEIMEC is a Brazilian national reference in the teaching and practice of medical acupuncture. With more than 3,000 physicians trained over 35 years, it collaborates with HC-FMUSP and is recognized by the Brazilian Medical College of Acupuncture (CMBA/AMB).

Published on 2024-12-18
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