Comparative Effectiveness of Acupuncture Versus Non-surgical Modalities for Treating Plantar Fasciitis: A Network Meta-Analysis

Asokumaran et al. · Cureus · 2024

🔍Network Meta-Analysis👥n=2,390🎯High Impact

Evidence Level

MODERATE
75/ 100
Quality
4/5
Sample
5/5
Replication
3/5
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OBJECTIVE

Compare the efficacy of acupuncture with other non-surgical therapies for plantar fasciitis

👥

WHO

2,390 adults with plantar fasciitis from 32 clinical studies

⏱️

DURATION

Follow-up of 1 to 3 months after treatment

📍

POINTS

Individualized points based on TCM theory and Ashi (阿是) points

🔬 Study Design

2390participants
randomization

Acupuncture

n=94

Traditional acupuncture or electroacupuncture

ESWT

n=840

Extracorporeal shock wave therapy

Corticosteroid injection

n=473

Local corticosteroid injection

PRP

n=216

Platelet-rich plasma

Ultrasound

n=53

Guided ultrasound therapy

Placebo

n=714

Placebo control

⏱️ Duration: 1 to 3 months of follow-up

📊 Results in numbers

-1.33 points VAS

Pain reduction with acupuncture (1 month)

PRP (-2.67 points)

Best treatment (3 months)

1st in pain reduction

Acupuncture efficacy (1 month)

p < 0.05 only for acupuncture

Statistical significance

📊 Outcome Comparison

Pain reduction (VAS) at 1 month vs placebo

Acupuncture
1.33
PRP
0.96
Ultrasound
0.75
ESWT
0.71
Corticosteroid
0.15
💬 What does this mean for you?

This large study showed that acupuncture is effective for reducing plantar fasciitis pain, especially in the first month of treatment. Although other therapies such as platelet-rich plasma are also effective, acupuncture proved to be a valid alternative and should be considered alongside other conventional treatments.

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Article summary

Plain-language narrative summary

Plantar fasciitis is a condition that causes intense pain in the heel region, primarily affecting adults who spend long periods standing. It is characterized by inflammation of the plantar fascia, a structure that supports the arch of the foot, causing excruciating pain especially during the first steps in the morning. This condition can be triggered by various factors, including obesity, inappropriate footwear, hard walking surfaces, and muscle weakness. Although several treatment options are available, there is no clear consensus on which approach is most effective.

First-line treatments include anti-inflammatory medications and physical therapy, while second-line options involve extracorporeal shock wave therapy, ultrasound, corticosteroid injections, and platelet-rich plasma. Recently, acupuncture has gained popularity as a therapeutic alternative, but studies directly comparing its efficacy with other non-surgical treatments were lacking.

This study aimed to determine whether acupuncture represents a viable alternative for the treatment of plantar fasciitis when compared with other therapeutic modalities. The researchers conducted a network meta-analysis, a sophisticated type of statistical analysis that allows multiple treatments to be compared directly and indirectly. Five scientific databases were analyzed, including PubMed, Google Scholar, and a Chinese database, covering the period from January 2000 to October 2020. Of the 1,258 studies initially identified, only 32 met the inclusion criteria, totaling 2,390 participants.

The rigorous criteria included adult patients with a medical diagnosis of plantar fasciitis, studies comparing at least two of the treatments of interest, and those using the visual analog pain scale as the primary measure. This scale, which ranges from 0 to 10, where zero represents no pain and ten represents unbearable pain, was chosen because it is the parameter most consistently used in the available studies.

The analysis revealed interesting results that varied according to follow-up time. After one month of treatment, acupuncture demonstrated the greatest pain reduction when compared with placebo, with a mean difference of -1.33 points on the pain scale. This result suggests that acupuncture was more effective than the other treatments in the short term. However, at three months of follow-up, the scenario changed significantly.

Platelet-rich plasma emerged as the treatment with the greatest pain reduction, presenting a difference of -2.67 points compared with placebo, followed by corticosteroid injections. It is important to highlight that, although these numbers suggest superiority of some treatments, the statistical analyses showed there were no statistically significant differences between treatments when compared with each other. This means that, from a scientific standpoint, all the treatments studied showed similar efficacy.

For patients suffering with plantar fasciitis, these results bring an encouraging perspective. Acupuncture can be considered a valid second-line treatment option, especially for those who have not been successful with initial conservative approaches or who prefer alternatives to medication. The efficacy demonstrated in the first month is particularly relevant, since many patients seek rapid symptom relief. For healthcare professionals, the study provides evidence that acupuncture can be integrated into the therapeutic arsenal for plantar fasciitis, offering patients another evidence-based alternative.

The decision about which treatment to choose can take into account factors such as patient preference, treatment availability, cost, and clinician experience. It is important that patients understand that different treatments may be more effective at distinct moments in the course of the disease.

The study has some important limitations that should be considered when interpreting the results. First, relatively few studies on acupuncture were included, mainly because research on this modality is less frequently published in English-language scientific journals. In addition, acupuncture studies face unique methodological challenges, such as the impossibility of conducting true double-blind studies, since neither the patient nor the acupuncture practitioner can be completely "blinded" to the treatment. The complexity and individualization of acupuncture also poses a challenge, since in Traditional Chinese Medicine treatment is personalized according to each patient's specific diagnosis, making the standardization required for rigorous scientific studies difficult.

Another limitation was the inability to assess long-term effects due to the scarcity of studies with prolonged follow-up. Finally, most studies analyzed isolated treatments, while in clinical practice it is common to combine different therapeutic modalities.

In conclusion, this pioneering study demonstrates that acupuncture is an effective and safe option for the treatment of plantar fasciitis, especially for short-term pain control. Patients and clinicians may consider acupuncture as a valid alternative alongside conventional treatments, with the choice being individualized considering patient preferences, availability, and clinician experience. It is important that treatment be performed by appropriately qualified professionals, since acupuncture requires specialized knowledge and extensive clinical practice. Although this study provides valuable evidence on the comparative efficacy of treatments, more long-term research is still needed to better understand the lasting benefits of acupuncture.

In addition, future studies investigating treatment combinations may offer even more relevant insights for clinical practice, since integrated approaches often provide better outcomes for patients.

Strengths

  • 1Large sample of 2,390 participants across 32 studies
  • 2First network meta-analysis comparing acupuncture with multiple therapies
  • 3Rigorous methodology using frequentist analysis
  • 4Inclusion of randomized and non-randomized studies
  • 5Risk-of-bias assessment using the ROBINS-I tool
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Limitations

  • 1Few acupuncture studies available in English
  • 2Impossibility of double-blinding in acupuncture studies
  • 3Variability in acupoint selection across studies
  • 4Analysis limited to short-term effects (1-3 months)
  • 5Lack of studies combining different treatment modalities
Dr. Marcus Yu Bin Pai

Expert Commentary

Dr. Marcus Yu Bin Pai

MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture

Clinical Relevance

Plantar fasciitis is one of the most frequent diagnoses in the musculoskeletal pain clinic, and the greatest challenge is not the diagnosis — it is deciding which therapeutic sequence to offer when the patient has already tried anti-inflammatories and insoles without satisfactory relief. This network meta-analysis with 2,390 participants and 32 studies fills a real gap by positioning acupuncture within a comparative ranking that includes ESWT, corticosteroids, and PRP in the same analysis. The operationally relevant finding is that acupuncture led the pain reduction at one month — exactly the time horizon when the patient is suffering most and most likely to abandon conservative treatment. For the physiatrist who needs to justify the indication of acupuncture as second-line before referring for injectable procedures or shock wave therapy, this analysis offers quantitative support with statistical significance, which until now was scarce in the comparative literature.

Notable Findings

The finding with greatest clinical weight is the temporal inversion of efficacy: acupuncture leads in the first month with a 1.33-point reduction on the VAS with p < 0.05 — being the only modality to reach statistical significance in this period — while PRP takes the lead at three months with a 2.67-point reduction. This temporal dynamic is biologically coherent: acupuncture acts early via modulation of nociceptive pathways and local neurogenic anti-inflammatory effect, while PRP depends on slower regenerative cascades mediated by growth factors. The statistical equivalence between treatments in direct comparisons reinforces that no modality absolutely dominates the therapeutic spectrum, legitimizing sequential strategies. The fact that only acupuncture reached p < 0.05 at one-month follow-up places this technique in a position of prominence for early symptom control.

From My Experience

In my practice at the pain and rehabilitation clinic, I typically observe a perceptible clinical response to acupuncture in plantar fasciitis between the third and fifth sessions — the patient reports improvement of morning pain, which is the most disabling symptom. I routinely work with protocols of eight to twelve sessions in the acute phase, combining needling of points KI-1, BL-60, and local pericircumferential points around the fascia insertion, frequently associating low-frequency electroacupuncture to potentiate the analgesic effect. I systematically integrate eccentric calf exercises and plantar stretching from the first consultation — in my assessment, acupuncture alone reduces pain, but without biomechanical rebalancing recurrence is frequent. For patients with elevated body mass index or those who work in prolonged standing positions, I usually combine with insole guidance, and when there is a trigger-point component in the gastrocnemius, I add dry needling of the muscle belly. I reserve PRP and shock wave therapy for refractory cases after this initial cycle.

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture.

Full original article

Read the full scientific study

Cureus · 2024

DOI: 10.7759/cureus.68959

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.