The effects of acupuncture combined with Western medicine in the treatment of neck, shoulder, lumbar, and leg pain
Shan et al. · American Journal of Translational Research · 2023
Evidence Level
MODERATEOBJECTIVE
To investigate the effects of traditional Chinese acupuncture combined with Western medicine in the treatment of neck, shoulder, lumbar, and leg pain
WHO
86 patients with neck, shoulder, lumbar, and leg pain
DURATION
4 weeks of treatment
POINTS
Quyuan, Bingfeng, Dazhui, Jiansan, Tianzong, Jianliao, Quchi, Hegu, Yanglingquan, Chengshan, Shenshu
🔬 Study Design
Control Group
n=43
Conventional Western medicine
Observation Group
n=43
Acupuncture + herbal fumigation + Western medicine
📊 Results in numbers
Efficacy rate - Combined Group
Efficacy rate - Control Group
Pain reduction (VAS) - Combined Group
Pain reduction (VAS) - Control Group
Percentage highlights
📊 Outcome Comparison
Pain Score (VAS) - post-treatment
Motor Function (Fugl-Meyer) - post-treatment
This study demonstrated that combining traditional Chinese acupuncture with conventional medications is more effective in treating neck, shoulder, lower back, and leg pain than using medications alone. The combined treatment significantly reduced pain and improved patients' range of motion.
Article summary
Plain-language narrative summary
Neck, shoulder, and lower back pain are very common problems that affect millions of people around the world. These complaints can have varied causes, ranging from muscle tension due to poor posture to more complex inflammatory processes. Conventional medical treatment has traditionally involved medications for pain relief, but the results are often not entirely satisfactory, especially when one considers prolonged use of these medications and their potential side effects. For this reason, interest has grown in integrative therapies that combine Western medicine approaches with traditional Chinese medicine practices, such as acupuncture, to offer more comprehensive and effective treatment.
The study in question was developed by Chinese researchers with the goal of evaluating whether the combination of acupuncture with conventional medications would be more effective than medication-only treatment for neck, shoulder, lower back, and leg pain. To do so, the researchers followed 86 patients over three years, dividing them into two groups. The first group, called the control group, received only standard medication treatment, including drugs such as muscle relaxants and anti-inflammatories. The second group, called the observation group, received the same medications, with the addition of acupuncture treatment and fumigation with Chinese medicinal herbs.
Both treatments lasted four consecutive weeks. The researchers evaluated several aspects, including pain level, range of motion, patients' quality of life, and inflammatory markers in the blood.
The results showed significant and promising differences for the group receiving the combined treatment. The treatment efficacy rate was considerably higher in the group receiving acupuncture together with medications, reaching more than 93% of cases with positive results, compared with approximately 77% in the group receiving medications alone. More importantly, patients in the combined group reported greater pain reduction, measured using a specific scale. Limb mobility also improved significantly more in the combined therapy group, as did specific functions of the neck, shoulders, and lower back.
The researchers also observed that inflammatory markers in the blood, including substances such as interleukin-6 and C-reactive protein, decreased more substantially in patients who received the integrated treatment.
From a clinical standpoint, these findings are especially relevant for both patients and health care professionals. For patients, the results suggest that combining acupuncture with conventional medications may offer more effective pain relief and functional improvement, potentially reducing the need for higher medication doses or longer treatment durations. This may mean less exposure to medication side effects while maintaining or even improving treatment efficacy. For health care professionals, the study provides scientific evidence supporting the integration of traditional Chinese medicine practices into the treatment of musculoskeletal conditions.
The combined approach proved safe and more effective, suggesting that integrative treatment protocols may be a valuable strategy for improving patient outcomes.
However, it is important to acknowledge the study's limitations for proper interpretation of the results. The number of participants, although appropriate for this type of research, is still relatively small, which may limit the generalizability of the results to larger and more diverse populations. In addition, the study was conducted at only one medical center in China, which may influence the results due to factors specific to that population or clinical setting. The researchers also did not follow patients for an extended period after treatment ended, leaving questions about the durability of the benefits observed.
Another important consideration is that the study did not analyze results separately for different types of pain, grouping neck, shoulder, and lower back pain as a single condition, when in clinical practice these can have distinct characteristics and treatment needs.
Despite these limitations, the study contributes valuably to the growing body of evidence on the efficacy of integrative medicine in the treatment of musculoskeletal pain. The results demonstrate that the careful combination of acupuncture with conventional medications can offer benefits superior to either treatment alone, both in terms of pain relief and functional improvement. For patients suffering from chronic neck, shoulder, or lower back pain, these findings may represent hope for more effective treatment, possibly with fewer adverse effects. It is important, however, that any decision regarding changes in treatment always be discussed with qualified health care professionals, who can evaluate each case individually and determine the most appropriate approach considering the specific characteristics of each patient.
Strengths
- 1Clear methodology with well-defined comparison groups
- 2Comprehensive evaluation including pain, motor function, and inflammatory markers
- 3Use of validated scales for outcome measurement
- 4Standardized treatment over 4 consecutive weeks
Limitations
- 1Single-center retrospective study with limited sample size
- 2Lack of randomization and blinding
- 3Lack of long-term follow-up of outcomes
- 4No subgroup analysis for different pain locations
Expert Commentary
Dr. Marcus Yu Bin Pai
MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture
▸ Clinical Relevance
Axial and lower-limb musculoskeletal pain represents a substantial share of outpatient volume in physiatry and pain services. This work by Shan et al. directly addresses the scenario in which the conventional pharmacologic arsenal — anti-inflammatories, muscle relaxants — delivers partial results after four weeks, a routine situation in practice. The 93.02% efficacy rate in the group that combined acupuncture and herbal fumigation with medication, against 76.74% in the pharmacologic-only group, reinforces the rationale for integrative protocols in patients with cervical, dorsal, and lumbar pain who have not fully responded to conventional treatment. Working populations with high postural demands, older adults with limitations on analgesic dose escalation, and patients with contraindications to full doses of anti-inflammatories are natural candidates for this combined strategy within a structured rehabilitation program.
▸ Notable Findings
The most striking data point is not just the difference in efficacy rates, but the magnitude of VAS score reduction: the combined group reached a score of 4.34±0.85 versus 5.24±0.49 in the control group at the end of four weeks, indicating that the combination not only widens the percentage of responders but also deepens the intensity of analgesia in each patient. Equally noteworthy is the more pronounced reduction in systemic inflammatory markers — interleukin-6 and C-reactive protein — in the combined therapy group, suggesting that acupuncture acts not only through central pain modulation but actively contributes to the resolution of the peripheral inflammatory substrate. This finding opens a relevant mechanistic window: acupuncture as a neuroinflammatory modulator, not merely a symptomatic analgesic, which justifies its use in more acute phases of the painful process.
▸ From My Experience
In my practice in the musculoskeletal pain clinic, the combination of acupuncture with baseline pharmacologic treatment has been the standard we adopt for patients with moderate to severe axial pain for at least a decade. I usually observe a clinically perceptible response between the third and fifth session — a two- to three-point reduction on the VAS is achievable in this interval when the protocol includes local and distal points with adequate stimulation. For discharge or transition to maintenance, the usual cycle ranges from eight to twelve sessions, with functional reassessment at the end. The herbal fumigation described in the article parallels the use of moxa that we associate in cases of pain with a cold-damp component, a pattern we frequently see in older patients and in workers exposed to cold. Patients with pure nociceptive pain and good adherence to medication respond better; profiles with a strong nociplastic component require a broader multimodal approach, including cognitive behavioral therapy.
Indexed scientific article
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Scientific Review

Marcus Yu Bin Pai, MD, PhD
CRM-SP: 158074 | RQE: 65523 · 65524 · 655241
PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.
Learn more about the author →Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.
Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.
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