NADA Ear Acupuncture: An Adjunctive Therapy to Improve and Maintain Positive Outcomes in Substance Abuse Treatment
Carter et al. · Behavioral Sciences · 2017
Evidence Level
MODERATEOBJECTIVE
To assess whether the NADA protocol combined with traditional treatment improves quality of life, depression, anxiety, and abstinence from substances
WHO
100 patients with substance use disorder (18-65 years) in an intensive outpatient program
DURATION
10-12 weeks of treatment with 6-month follow-up
POINTS
5 bilateral ear points: Shen Men, Sympathetic, Kidney, Liver, and Lung
🔬 Study Design
NADA + Traditional
n=50
NADA auricular acupuncture 2x/week + standard treatment
Control
n=50
Traditional treatment only (individual and group therapy)
📊 Results in numbers
Quality of life improvement (Q-LES) NADA group
Reduction in alcohol use at 3 months - NADA
Reduction in alcohol use at 3 months - Control
Post-discharge employment rate - NADA
Post-discharge employment rate - Control
Percentage highlights
📊 Outcome Comparison
Alcohol use at 6 months
Tobacco use at 6 months
This study showed that NADA auricular acupuncture, when combined with conventional treatment for substance use disorder, can help you feel better, find work more easily, and stay away from alcohol and tobacco for longer. It is a safe and relaxing treatment that complements other therapies.
Article summary
Plain-language narrative summary
This randomized controlled trial investigated the efficacy of the NADA (National Acupuncture Detoxification Association) protocol as an adjunctive therapy in the treatment of substance use disorder. The NADA protocol is one of the most commonly used forms of acupuncture in the United States, involving bilateral needle insertion at five specific ear points: Shen Men, Sympathetic, Kidney, Liver, and Lung. The study was conducted at Keystone Substance Abuse Services in South Carolina between July 2015 and March 2016. One hundred patients diagnosed with substance use disorder were randomized into two groups: 50 received traditional treatment plus NADA, and 50 received traditional treatment only.
Traditional treatment included individual therapy, 12-step counseling, and various group therapies for both groups. NADA group patients received auricular acupuncture twice weekly in 45-minute sessions of up to 20 patients per group, for an average of 8.3 weeks. Needles remained in place for 30-45 minutes per session. Outcomes were assessed using standardized questionnaires administered at baseline and end of program, including the Generalized Anxiety Disorder scale (GAD-7), Patient Health Questionnaire (PHQ-9) for depression, and the Quality of Life, Enjoyment, and Satisfaction Questionnaire (Q-LES).
Data were also collected on alcohol, drug, and tobacco use, as well as healthcare utilization at program completion and at 3- and 6-month follow-up. Main findings demonstrated significant benefits for the NADA group across multiple dimensions. With respect to quality of life, only the NADA group showed statistically significant improvement in Q-LES scores. NADA group patients reported feeling better about themselves and having more energy compared with the control group.
As for employment, 71% of unemployed NADA group patients obtained some type of work after discharge, compared with only 35% in the control group. Abstinence outcomes were particularly striking. At 3 months post-discharge, only 4% of the NADA group reported alcohol use versus 25% of the control group. At 6 months, this difference persisted, at 5% versus 50%, respectively.
For tobacco, at 6 months, only 7% of the NADA group continued smoking compared with 39% of the control group. Both groups showed similar improvements in anxiety and depression, but the NADA group demonstrated additional benefits on specific items such as energy and self-esteem. Interestingly, the study revealed that higher-risk populations (non-white, with criminal history, initial positive drug test) were more likely to complete the program when they participated in NADA treatment. The authors speculate that the observed benefits may be related to the physiological effects of acupuncture, including changes in neurotransmitter production and the body's regulatory system.
The NADA protocol induces a sense of "stillness" similar to the relaxation response experienced in mind-body therapies, but in a more passive way, which may be especially beneficial during early withdrawal when capacity for active participation may be impaired. Study limitations include the sample size without prior statistical calculation, high follow-up loss rate, and legal restrictions that limited the frequency of NADA treatments. Despite these limitations, the findings suggest that the NADA protocol may be a valuable addition to substance use treatment programs, offering unique benefits that complement traditional approaches.
Strengths
- 1Well-structured randomized controlled design
- 2Multiple clinically relevant outcomes assessed
- 3Long-term follow-up (6 months)
- 4High-risk population representative of clinical practice
Limitations
- 1Sample size without prior statistical calculation
- 2High follow-up loss rate (45% at 6 months)
- 3Limited frequency of NADA treatments due to legal restrictions
- 4Inability to blind participants
Expert Commentary
Prof. Dr. Hong Jin Pai
PhD in Sciences, University of São Paulo
▸ Clinical Relevance
The NADA protocol occupies a therapeutic space that conventional pharmacology and psychotherapy rarely manage to fill on their own: modulation of the patient's internal state in the first days and weeks of abstinence, precisely when the capacity for active engagement is most precarious. The employment data — 71% versus 35% — are a robust functional proxy of social reintegration, an outcome that any clinician recognizes as decisive for sobriety maintenance. The greater benefit profile in higher-risk populations, including patients with criminal history and initial positive drug test, indicates that NADA may be particularly valuable precisely where the conventional arsenal shows the lowest adherence rate. For physicians working in therapeutic communities or addiction outpatient services, this finding justifies incorporating the protocol as a structural component of the program, not as a second-line resource.
▸ Notable Findings
The divergence in alcohol abstinence outcomes throughout follow-up is the most striking finding of the study: 4% versus 25% at three months, widening to 5% versus 50% at six months. This pattern of growing separation between groups suggests not only an acute effect of auricular stimulation but a consolidation of neurobiological mechanisms — possibly related to neurotransmitter regulation and the relaxation response induced by Shen Men, Sympathetic, and Kidney points — that persist after treatment completion. Equally relevant is the improvement in Q-LES quality-of-life scores exclusively in the NADA group, with specific items such as energy and self-esteem standing out. These domains, often neglected in classical addiction follow-up instruments, play a central role in motivation to maintain abstinence.
▸ From My Experience
In my practice, the NADA protocol is one of the most underrated tools for supporting patients in withdrawal distress. I have observed that the subjective response — reduced agitation, improved sleep, sense of "grounding" — usually appears as early as the first two to three sessions, which greatly facilitates adherence to subsequent stages of treatment. I usually combine NADA with autonomic regulation techniques such as biofeedback and guided mindfulness, especially during the first four weeks. The patient profile that responds best, in my experience, is exactly the one described in this article: high anxiety in the early phase, difficulty with verbal engagement, and a sense of internal loss of control. I do not recommend the protocol in isolation for cases with severe non-stabilized psychiatric comorbidity. The group dynamic of NADA sessions — up to twenty patients in shared silence — has a therapeutic cohesion effect that complements, without replacing, individual work.
Full original article
Read the full scientific study
Behavioral Sciences · 2017
DOI: 10.3390/bs7020037
Access original articleScientific Review

Marcus Yu Bin Pai, MD, PhD
CRM-SP: 158074 | RQE: 65523 · 65524 · 655241
PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.
Learn more about the author →Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.
Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.
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