Effects of Trigger Point Dry Needling on Neuromuscular Performance and Pain of Individuals Affected by Patellofemoral Pain: A Randomized Controlled Trial

Ma et al. · Journal of Pain Research · 2020

🔬Parallel RCT👥n=50 participants🎯Moderate Evidence

Evidence Level

MODERATE
75/ 100
Quality
4/5
Sample
3/5
Replication
3/5
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OBJECTIVE

To assess the effects of dry needling at quadriceps trigger points on pain and function in patients with patellofemoral pain syndrome

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WHO

50 patients with patellofemoral pain syndrome, ages 18-40 years

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DURATION

6 weeks of treatment with 3-month follow-up

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POINTS

Trigger points in the vastus medialis obliquus, vastus lateralis, and rectus femoris muscles

🔬 Study Design

50participants
randomization

Dry Needling

n=25

Dry needling at trigger points + stretching exercises

Placebo

n=25

Sham needling + stretching exercises

⏱️ Duration: 6 weeks

📊 Results in numbers

46.67 to 10.48

Pain reduction in treatment group (6 weeks)

66.42 to 90.68

Kujala functional improvement (6 weeks)

3 months

Maintenance of benefits

0.79 to 0.91

Improved VMO/VL ratio

📊 Outcome Comparison

Visual Analog Scale (VAS) - 6 weeks

Dry Needling
10.48
Placebo
24.77

Kujala Scale - 6 weeks

Dry Needling
90.68
Placebo
77.85
💬 What does this mean for you?

This study showed that dry needling at painful trigger points in the thigh muscle (quadriceps) can significantly reduce knee pain and improve function in people with patellofemoral pain syndrome. The benefits were maintained for at least 3 months after treatment, offering an effective therapeutic option for this common condition.

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Article summary

Plain-language narrative summary

Patellofemoral pain syndrome (PFPS) is one of the most common causes of knee pain in young adults, accounting for 25-30% of cases seen in sports medicine clinics. This condition, characterized by diffuse pain behind and around the patella, is aggravated by activities such as squatting, prolonged sitting, and climbing stairs, significantly impacting the ability to exercise and perform daily activities. This randomized controlled trial investigated the efficacy of trigger point dry needling (TrP-DN) as a treatment for this debilitating condition. The research involved 50 patients diagnosed with PFPS, ages 18 to 40 years, who were randomized into two groups of 25 participants each.

The experimental group received dry needling targeting active trigger points in the vastus medialis obliquus, vastus lateralis, and rectus femoris muscles, while the control group received sham (placebo) needling. Both groups performed daily static stretching exercises of the quadriceps. The treatment protocol consisted of one session per week for 6 weeks, followed by 3 months of follow-up. Trigger points were identified using specific criteria including the presence of a palpable taut band, pain reproduction with compression, local twitch response, and referred pain.

The needling technique followed the "fast-in/fast-out" method described by Hong, using disposable stainless-steel needles. The results demonstrated significant superiority of real dry needling compared with placebo. In the treated group, the visual analog scale (VAS) for pain decreased from 46.67 points at baseline to 10.48 points after 6 weeks of treatment, remaining at 6.19 points after 3 months. In contrast, the placebo group showed a smaller and unsustained reduction.

Function, assessed by the Kujala scale, showed remarkable improvement in the experimental group, increasing from 66.42 to 90.68 points at 6 weeks and remaining at 92.21 points at the 3-month follow-up. Particularly interesting was the assessment of neuromuscular coordination through the VMO/VL (vastus medialis obliquus/vastus lateralis) ratio, measured by surface electromyography during isokinetic contractions. This ratio is considered an important indicator of muscle balance in the quadriceps and is frequently altered in PFPS. The treated group showed significant improvement in this ratio, increasing from 0.79 to 0.91, while the placebo group showed no significant changes.

The clinical implications of this study are substantial. Dry needling offers a specific and effective therapeutic approach to treating myofascial trigger points that contribute to pain and dysfunction in PFPS. The technique demonstrated not only symptomatic relief, but also improvement in neuromuscular function, suggesting benefits that go beyond simple pain control. The maintenance of benefits for 3 months indicates the potential for lasting effects.

The proposed mechanism involves interrupting the vicious cycle of muscle contracture, local ischemia, and nociceptive sensitization characteristic of trigger points. Precise needling of these points may restore local microcirculation, reduce excessive acetylcholine release, and normalize neuromuscular junction function. However, the study presents some important limitations. The sample size of 50 participants, although statistically adequate, is relatively small for broad generalization of results.

The lack of a record of the exact number of trigger points treated in each participant may have introduced variability into the results. Additionally, supervision of home-based stretching exercises was limited, which could influence outcomes. The neuromuscular coordination assessment was restricted to a single angular velocity (60°/s), not exploring other velocities or isometric contractions.

Strengths

  • 1Randomized controlled design with appropriate placebo group
  • 2Long-term follow-up (3 months) demonstrating sustainability of benefits
  • 3Objective assessment of neuromuscular coordination via electromyography
  • 4Clear criteria for trigger point identification and treatment
  • 5Multiple outcome measures including pain, function, and biomechanics
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Limitations

  • 1Moderate sample size (n=50) limiting generalizability
  • 2Lack of record of the specific number of trigger points treated per participant
  • 3Limited supervision of home stretching exercises
  • 4Electromyographic assessment restricted to a specific angular velocity
  • 5Absence of a no-intervention control group to assess the isolated effect of needling
Dr. Marcus Yu Bin Pai

Expert Commentary

Dr. Marcus Yu Bin Pai

MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture

Clinical Relevance

Patellofemoral pain syndrome represents one of the most frequent diagnoses in physiatry and sports medicine practices, particularly in physically active young adults, and the search for strategies that act on peripheral pain mechanisms — and not only on the symptom — has been a growing clinical priority. This trial directly contributes to that scenario by demonstrating that dry needling of trigger points in the vastus medialis obliquus, vastus lateralis, and rectus femoris produces meaningful pain reduction and functional gain sustained for three months, consistently outperforming placebo. In practice, this means that patients with anterior knee pain refractory to exclusively kinetic protocols have, in this technique, a well-supported adjunctive resource. Integration with static quadriceps stretching reinforces the feasibility of a combined model that is easily implementable in outpatient rehabilitation services.

Notable Findings

The most robust finding of the study is not the pain reduction itself — which is expected — but the improvement in the VMO/VL ratio measured by surface electromyography, which rose from 0.79 to 0.91 after six weeks in the treated group. This objective change in quadriceps neuromuscular balance indicates that dry needling does not operate solely through immediate analgesic mechanisms, but also interferes with the coordination of periarticular muscle activation — a finding with direct biomechanical implications for patellar tracking. Adding to this, the maintenance of the Kujala score at 92.21 points at three months, starting from 66.42 at baseline, points to functional durability that extends beyond the active treatment period. The pain trajectory in the experimental group — from 46.67 to 10.48 on the VAS — sustained at 6.19 at late follow-up, suggests that deactivation of trigger points generates a reset of the peripheral ischemia-sensitization cycle with prolonged effect.

From My Experience

In my practice in the musculoskeletal pain clinic, PFPS with a prominent myofascial component is recognizable by the distribution of referred pain on compression of the vastus lateralis and by the local twitch response to needling — a pattern I usually identify on the initial assessment. I have observed that clinical response typically emerges between the second and third session, with patients reporting reduced pain on axial-load activities even before completing the protocol. For functional consolidation, I usually work with six to eight weekly sessions followed by biweekly maintenance for two months. The combination I most often use pairs dry needling of the vasti with supervised eccentric strengthening and patellofemoral mobilization — the stand-alone technique delivers analgesia, but it is the proper motor recruitment that sustains the result. Sedentary patients with chronic quadriceps shortening and young athletes with recently increased training load respond best. I avoid recommending the technique as monotherapy in cases with a predominant structural component, such as significant trochlear dysplasia.

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture.

Full original article

Read the full scientific study

Journal of Pain Research · 2020

DOI: 10.2147/JPR.S240376

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Scientific Review

Marcus Yu Bin Pai, MD, PhD

Marcus Yu Bin Pai, MD, PhD

CRM-SP: 158074 | RQE: 65523 · 65524 · 655241

PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.

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Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.

Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.