The Effectiveness of Cupping Therapy on Relieving Chronic Neck and Shoulder Pain: A Randomized Controlled Trial
Chi et al. · Evidence-Based Complementary and Alternative Medicine · 2016
Evidence Level
MODERATEOBJECTIVE
Investigate the efficacy of cupping therapy in relieving chronic neck and shoulder pain
WHO
60 adults with chronic neck and shoulder pain for at least 3 months
DURATION
Single 20-minute session
POINTS
SI-15 (Jianzhongshu), GB-21 (Jianjing), and LI-15 (Jianyu)
🔬 Study Design
Cupping therapy
n=30
Fire cupping at SI-15, GB-21, and LI-15 for 20 minutes
Control
n=30
20-minute rest with no intervention
📊 Results in numbers
Reduction in neck pain (cupping therapy)
Reduction in shoulder pain (cupping therapy)
Increase in skin temperature at GB-21
Statistical significance
📊 Outcome Comparison
Neck pain intensity (post-treatment)
Shoulder pain intensity (post-treatment)
This study showed that cupping therapy (the use of fire cupping) can significantly reduce neck and shoulder pain in just one 20-minute session. The treatment increased skin temperature in the area, improving blood circulation and providing pain relief without major side effects.
Article summary
Plain-language narrative summary
Chronic neck and shoulder pain (CNSP) is a common musculoskeletal condition affecting 16% to 78% of the general population, especially prevalent in middle-aged and older adults. This condition can significantly impact quality of life, affecting social activities, future plans, and the emotional well-being of families. Cupping therapy, an ancient technique of traditional Chinese medicine recognized by the World Health Organization, has been used worldwide as a complementary treatment for various pain conditions. This single-blind randomized controlled trial investigated the immediate efficacy of cupping therapy in relieving CNSP, focusing on changes in skin surface temperature as a physiological indicator of therapeutic effects.
The research was conducted in Taiwan between October 2012 and February 2013, recruiting 60 participants through community advertisements. Inclusion criteria required participants to work at least 40 hours per week and to have suffered work-related pain continuously for at least 3 consecutive months, with a minimum intensity of 3 points on the visual analog scale (VAS). Individuals with infection, injury, or bleeding in the skin of the treatment area, cervical neuropathy, use of analgesics in the preceding 4 hours, or caffeine consumption in the same period were excluded. Participants were randomized into two groups of 30 each.
The cupping therapy group received fire cupping at three specific acupuncture points: SI-15 (Jianzhongshu), located in the back about 3-4 cm lateral to the lower edge of the spinous process of the seventh cervical vertebra; GB-21 (Jianjing), located at the midpoint between the dazhui point and the acromion of the shoulder; and LI-15 (Jianyu), located on the lateral aspect of the arm in the deltoid muscle. The procedure consisted of applying medium glass cups (4 cm in diameter, 260 mL volume) for 10 minutes on each side of the body, totaling 20 minutes of treatment. The control group rested for the same period. Measurements were performed using a FLIR ThermaCAM infrared camera for skin surface temperature, a mercury sphygmomanometer for blood pressure, and a visual analog scale for pain intensity.
Skin temperature was recorded at 5-minute intervals, while pain was assessed through specific neck movements (flexion, rotation, lateral bending) and shoulder movements (arm elevation, extension). The results demonstrated significant efficacy of cupping therapy. Skin surface temperature increased at all three acupuncture points in the cupping therapy group: SI-15 increased from 30.7°C to 32.8°C (an increase of 2.1°C); GB-21 from 30.6°C to 32.7°C (an increase of 2.1°C); and LI-15 from 29.4°C to 31.1°C (an increase of 1.7°C). The control group showed no significant changes in temperature.
As for pain, neck pain intensity decreased dramatically from 9.7 to 3.6 points in the cupping therapy group (a 6.1-point reduction), while in the control group it decreased only from 9.7 to 9.5 (a 0.2-point reduction). Shoulder pain also improved significantly, decreasing from 8.5 to 2.6 points in the treatment group (a 5.9-point reduction) versus 8.5 to 7.9 points in the control group (a 0.6-point reduction). All differences between groups were statistically significant (p < 0.001). Systolic blood pressure also decreased in the cupping therapy group, from 117.7 to 111.8 mmHg.
Mechanistically, cupping therapy promotes local vasodilation, increasing blood flow in the treated area. This effect results in hyperemia, a sensation of warmth, and accelerated elimination of toxins and metabolic waste, improving local physical function. The increase in skin temperature observed confirms these physiological effects and correlates with the pain relief reported by participants. The clinical implications are promising, suggesting that cupping therapy may be an effective and safe alternative to analgesics for chronic neck and shoulder pain.
The treatment was well tolerated, with only two participants reporting mild low back pain related to the seated position, and no other adverse effects. No participant developed localized burns or adverse reactions in the treated areas, confirming the safety of the procedure when performed appropriately. The limitations of the study include the relatively small sample size, female predominance (91.7% women), evaluation of only one treatment session without long-term follow-up, and the inability to fully blind because of the nature of the intervention. Future studies should investigate multiple sessions, larger samples with balanced sex and age distribution, and prolonged follow-up to assess the durability of effects.
This study contributes significantly to the scientific evidence on cupping therapy, providing objective data on its physiological and therapeutic effects and supporting its integration as a complementary therapy in the management of chronic musculoskeletal pain.
Strengths
- 1Randomized controlled design with an adequate control group
- 2Objective temperature measurements with infrared camera
- 3Well-defined protocol with specific acupuncture points
- 4Rigorous statistical analysis with ANCOVA
- 5No serious adverse effects reported
Limitations
- 1Small sample (n=60) with female predominance
- 2Single-session evaluation without follow-up
- 3Inability to use double-blinding because of the nature of the intervention
- 4Lack of a placebo group with sham intervention
Expert Commentary
Dr. Marcus Yu Bin Pai
MD, PhD · Pain Medicine · Physical Medicine and Rehabilitation · Medical Acupuncture
▸ Clinical Relevance
Work-related chronic neck and shoulder pain is one of the most frequent presentations in physiatry and pain medicine services. This randomized controlled trial, conducted in workers with at least 40 hours per week of work and three continuous months of pain, offers objective data on fire cupping at anatomically precise points — SI-15, GB-21, and LI-15 — which correspond to areas of high trigger point density in the upper trapezius and deltoid. The magnitude of analgesic reduction observed — more than six points on the visual analog scale for neck pain — in a single 20-minute session positions the technique as a rapid-effect adjunctive resource, particularly useful in acute pain crises against a chronic background. Office workers, professionals with postural overload, and patients who do not tolerate or have contraindications to anti-inflammatories are natural candidates for this approach within a multimodal rehabilitation program.
▸ Notable Findings
The most robust finding of this work is the thermographic objectivity: the infrared camera documented an elevation of 2.1°C at SI-15 and GB-21, confirming measurable local vasodilation rather than just a self-reported improvement. This correlation between induced cutaneous hyperemia and reduction in pain intensity provides concrete physiological substrate for the proposed mechanism of action — increased local blood flow, clearance of algogenic metabolites, and peripheral nociceptive modulation. Another finding worth attention is the reduction in systolic blood pressure from 117.7 to 111.8 mmHg in the treatment group, suggesting an autonomic effect that goes beyond local analgesia. The response at LI-15, although with slightly smaller thermal elevation (1.7°C), reinforces the relevance of the periarticular shoulder component in treating this syndrome, a finding often underestimated when therapeutic focus falls exclusively on cervical paravertebral musculature.
▸ From My Experience
In my practice in the musculoskeletal pain clinic, cupping therapy enters as an adjunctive tool — never as monotherapy — especially in the patient who is locked up, with exuberant local hypersensitivity that makes even palpation for dry needling at upper trapezius trigger points difficult. I usually see noticeable relief as early as the first session, but consolidation of the analgesic effect that allows progress in active rehabilitation typically appears between the third and fifth sessions, when combined with eccentric exercise for the posterior cervical chain. The profile that responds best is exactly the one described in this work: chronic postural overload, moderate to severe pain, without dominant radicular component. I avoid the technique in patients on anticoagulants, those with significant capillary fragility, or active dermatologic disease in the area. The blood pressure reduction documented in the study echoes what I observe clinically — patients frequently report a sensation of systemic relaxation after the session, something I attribute to vagal modulation secondary to regional somatic analgesia.
Full original article
Read the full scientific study
Evidence-Based Complementary and Alternative Medicine · 2016
DOI: 10.1155/2016/7358918
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Marcus Yu Bin Pai, MD, PhD
CRM-SP: 158074 | RQE: 65523 · 65524 · 655241
PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.
Learn more about the author →Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.
Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.
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