Acupuncture: a new method to treat tic disorders in children
Geng et al. · Traditional Medicine Research · 2022
Evidence Level
MODERATEOBJECTIVE
To review the efficacy, mechanisms, and specific methods of acupuncture in the treatment of tic disorders in children
WHO
Children with tic disorders, including Tourette syndrome
DURATION
Historical review from 26 BCE to current studies
POINTS
Baihui (GV-20 百会), Sishencong (EX-HN-1 四神聪), Shenmen (HT-7 神门), Neiguan (PC-6 内关), Fengchi (GB-20 风池), Zusanli (ST-36 足三里)
🔬 Study Design
Narrative review
n=0
Analysis of multiple acupuncture studies
📊 Results in numbers
YGTSS reduction (acupuncture vs haloperidol)
Recurrence rate (acupuncture vs medication)
Electroacupuncture vs medication efficacy
Total efficacy rate (traditional acupuncture)
Percentage highlights
📊 Outcome Comparison
Total Efficacy Rate
Recurrence Rate (6 weeks)
This study shows that acupuncture is a safe and effective option for children with tics, and may be used alone or alongside medications. Acupuncture significantly reduced tics and had fewer relapses than conventional treatments, offering a valuable alternative for families seeking less invasive therapies.
Article summary
Plain-language narrative summary
Tic disorders are neurological conditions that affect children and can significantly impact their quality of life. Characterized by involuntary, sudden, and repetitive movements or sounds, these disorders were first described by the French neurologist Gilles de la Tourette in 1885. They currently affect approximately 0.3% to 1% of the world population and are three to four times more common in boys. The problem extends beyond physical symptoms, as children frequently face misunderstanding and social stigma, which also affects their emotional and psychological health.
Conventional treatment of tic disorders presents considerable challenges. The medications traditionally used, such as clonidine, risperidone, tiapride, and haloperidol, can cause significant side effects and require good patient cooperation, which can be difficult for younger children. Behavioral therapies and deep brain stimulation are also options, but each has its own limitations. Faced with these difficulties, researchers have investigated therapeutic alternatives, with acupuncture among the most promising.
In traditional Chinese medicine, these disorders are classified as chronic inflammatory convulsions, and acupuncture has shown good efficacy in relieving spasticity with few adverse effects.
This study reviewed the existing scientific literature on the use of acupuncture for the treatment of tic disorders in children, analyzing both clinical research and experimental animal studies. The researchers examined different acupuncture modalities, including traditional Chinese acupuncture, electroacupuncture, scalp acupuncture, and auricular acupuncture. The aim was to assess the efficacy of these treatments, understand the mechanisms of action, and compare results with conventional drug therapies. The methodology involved analysis of studies that used standardized scales such as the Yale Global Tic Severity Scale (YGTSS) to measure symptom improvement.
The research findings are encouraging and reveal that acupuncture may be an effective alternative for the treatment of tic disorders. Clinical studies showed that acupuncture, when used alone, may be more effective than medications such as haloperidol, tiapride, and aripiprazole, with fewer side effects. When combined with medications, acupuncture enhances treatment benefits and reduces the incidence and severity of medication-related adverse effects. A particularly interesting aspect is that the therapeutic effects of acupuncture appear to be more durable, with a lower relapse rate during follow-up periods of six weeks to six months.
Mechanistically, research suggests that acupuncture acts by regulating brain neurotransmitters, including dopamine, norepinephrine, serotonin, and gamma-aminobutyric acid (GABA), substances fundamental to movement control that are altered in tic disorders.
For patients and clinicians, these findings offer important perspectives for the treatment of tic disorders. Acupuncture presents itself as an especially valuable option for children who do not respond well to conventional medications or who experience significant side effects. For mild cases of tic disorder, especially those diagnosed early, acupuncture may be used as the primary treatment, providing symptom relief and reducing anxiety for both the child and the parents. In more severe cases such as Tourette syndrome, combining acupuncture with medications may maximize therapeutic benefits.
The flexibility of acupuncture treatment, which allows adjustments in session timing and frequency, makes it particularly well suited to the pediatric setting.
It is important to acknowledge the limitations of this research area. Most studies did not include placebo control groups, which raises questions about whether part of the observed improvement could be due to the natural remission of symptoms that occurs in some cases of tic disorders. In addition, ethical considerations make it difficult to conduct placebo-controlled studies in this population. Research on the mechanisms of action of acupuncture is still in early stages, focusing mainly on effects on neurotransmitters but not fully exploring how the technique influences the nervous and immune systems.
Regarding safety, although acupuncture is generally well tolerated, minor complications such as bleeding or bruising may occur, requiring experienced practitioners familiar with pediatric anatomy. More multicenter studies with larger samples are needed to establish more precise treatment protocols and definitively validate the efficacy of acupuncture for tic disorders in children.
Strengths
- 1Comprehensive review including multiple acupuncture types
- 2Analysis of neurobiological mechanisms of acupuncture
- 3Comparison with established pharmacological treatments
- 4Assessment of safety and adverse events
Limitations
- 1Absence of placebo control groups in the reviewed studies
- 2Need for more research on specific mechanisms
- 3Variability in acupuncture protocols across studies
- 4Ethical limitations in placebo-controlled studies
Expert Commentary
Prof. Dr. Hong Jin Pai
PhD in Sciences, University of São Paulo
▸ Clinical Relevance
Tic disorders represent a genuine therapeutic challenge in pediatric practice, and this review consolidates evidence that legitimizes acupuncture as an option within the available therapeutic armamentarium. The most immediate clinical scenario for application is the child with moderate tics who does not tolerate the adverse effects of haloperidol, risperidone, or tiapride — excessive sedation, weight gain, extrapyramidal symptoms — or whose parents justifiably resist prolonged use of dopaminergic medications. Electroacupuncture, with a 96.88% efficacy rate versus 87.50% for the comparator medication, and traditional acupuncture with 89.80% overall efficacy, place the technique at a competitive level. Even more clinically relevant is the recurrence rate: 3.3% with acupuncture versus 45.2% with medication, suggesting that benefit is sustained beyond the active treatment period — an important data point for long-term therapeutic planning in this population.
▸ Notable Findings
The finding that most deserves attention is not just the point efficacy but the durability of the response. The relapse rate of 3.3% versus 45.2% in the medication group, assessed at six weeks to six months of follow-up, indicates that acupuncture may be promoting a more stable functional reorganization of the cortico-striato-thalamo-cortical circuits involved in tic pathophysiology. This is consistent with the proposed neurobiological mechanisms: modulation of dopamine, norepinephrine, serotonin, and GABA — the same molecular targets as established pharmacotherapies, but via non-pharmacological pathways. The review also shows that combining acupuncture with medication reduces both the incidence and severity of pharmacological adverse effects, opening space for dose-reduction strategies. The multimodal approach — scalp acupuncture, auricular acupuncture, and electroacupuncture — diversifies the tools available according to the child's profile and cooperation.
▸ From My Experience
In my practice with pediatric patients referred to the service for tics that persist despite medication or because of intolerance to it, I typically observe a perceptible initial response between the third and fifth sessions — reduction in the frequency and intensity of simple motor tics usually precedes improvement in vocal tics. I generally work with cycles of twelve to sixteen sessions for the intensive phase, followed by biweekly maintenance for two to three months. Electroacupuncture at Liver and Heart meridian points, combined with scalp acupuncture in the motor and sensory zones, has been my preferred combination. I reserve an acupuncture-only approach for mild-to-moderate cases with recent diagnosis; in established Tourette syndrome, combination with medication is the approach I adopt. Anxious children with an associated hyperactivity profile respond less consistently in the early sessions, requiring patience and progressive technical adjustment.
Full original article
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Traditional Medicine Research · 2022
DOI: 10.53388/TMR20220127259
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Marcus Yu Bin Pai, MD, PhD
CRM-SP: 158074 | RQE: 65523 · 65524 · 655241
PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.
Learn more about the author →Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.
Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.
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