Auricular Acupuncture: A Potential Treatment for Anxiety
Wang et al. · Anesthesia & Analgesia · 2001
Evidence Level
MODERATEOBJECTIVE
Evaluate whether auricular acupuncture can reduce acute anxiety in healthy volunteers
WHO
55 health professionals, 27-64 years, with no history of psychiatric illness
DURATION
48 hours of treatment with assessments at 30 min, 24 h, and 48 h
POINTS
Shenmen, relaxation point on the ear, and placebo point
🔬 Study Design
Shenmen
n=22
Acupuncture at the bilateral shenmen point
Relaxation
n=15
Acupuncture at the bilateral relaxation point
Placebo
n=18
Acupuncture at a point without anxiolytic effect
📊 Results in numbers
Anxiety reduction at 30 minutes (relaxation group vs others)
Anxiety reduction at 24 hours (relaxation group vs others)
Significant difference between groups
📊 Outcome Comparison
Anxiety levels (STAI) at 30 minutes
This study showed that auricular (ear) acupuncture can reduce anxiety quickly and effectively. The effect started in just 30 minutes and lasted up to 48 hours, suggesting that this technique can be useful for people who experience anxiety in specific situations, such as before surgery.
Article summary
Plain-language narrative summary
Anxiety is a common experience that affects millions of people, especially in medical situations such as surgical procedures. Up to eighty percent of adult patients may experience intense anxiety levels before surgery, which can negatively affect their postoperative recovery. Currently, available treatments include sedative medications and psychological preparation programs, but both represent high costs for the healthcare system. Medications can have lasting side effects, while psychological programs are time-consuming and not always effective.
Faced with this scenario, researchers at Yale University investigated a promising and low-cost alternative: auricular acupuncture, a technique that applies stimuli to specific points on the ear.
This study was conducted as a randomized controlled clinical trial involving 55 healthy health professionals, aged between 27 and 64, who had never received acupuncture before. Participants were divided into three distinct groups to compare different auricular acupuncture points. The first group received acupuncture at the "Shenmen" point, considered a master point for relaxation in traditional Chinese medicine. The second group was treated at the specific "Relaxation" point, documented in French texts on auricular acupuncture.
The third group served as a control, receiving acupuncture at a "placebo" point that has no known anxiolytic properties. The treatment was applied to both ears using special pressure needles that remained in place for 48 hours. During this period, the researchers measured anxiety levels using scientifically validated questionnaires, in addition to monitoring physiological signs such as blood pressure, heart rate, and skin electrodermal activity.
The results revealed that auricular acupuncture can effectively reduce anxiety in healthy individuals. Specifically, participants who received treatment at the "Relaxation" point showed a significant reduction in anxiety levels compared with the other two groups. This improvement was observed as early as 30 minutes after needle application, was maintained for 24 hours, and was still detectable after 48 hours. Interestingly, the "Shenmen" point, traditionally considered important for relaxation, did not demonstrate as pronounced an effect as the specific Relaxation point.
Regarding the physiological parameters measured, there were no significant differences between the groups in blood pressure, heart rate, or electrodermal activity. The researchers explain that this was expected, since the healthy volunteers did not present elevated physiological stress levels at baseline, making it difficult to detect changes in these parameters.
For patients facing anxiety related to medical procedures, these results offer hope for a new therapeutic option. Auricular acupuncture has several practical advantages: it is technically simple to apply, requires less expertise than traditional body acupuncture, has a very low cost compared with sedative medications, and may be more acceptable to patients who prefer to avoid medication. The fact that the effect begins quickly, in only 30 minutes, makes this technique suitable for the hospital environment, where time is often limited. In addition, since the benefit can last up to 48 hours while the needles remain in place, there is the possibility that auricular acupuncture may also help control anxiety after surgical procedures.
For health professionals, this research suggests that auricular acupuncture can be a valuable complementary tool in managing patient anxiety, especially given its favorable safety profile and reduced cost.
It is important to recognize the limitations of this initial study. The research was conducted with healthy health professionals in their normal work environment, not with patients actually anxious before medical procedures. The authors themselves recognize that the anxiety experienced by healthy individuals in everyday life may differ from the intense preoperative anxiety that patients face. In addition, the relatively small size of each group and the unequal distribution of characteristics such as age and gender may have influenced the results.
Despite these limitations, the researchers consider the results to be promising enough to justify future studies with real surgical patients. Although we still do not fully understand how auricular acupuncture produces its anxiolytic effects, theories suggest that it may alter brain chemistry, possibly affecting neurotransmitters such as serotonin, which plays a fundamental role in mood and anxiety regulation. This study represents an important first step toward more accessible and natural treatments for anxiety in medical contexts.
Strengths
- 1First study to objectively evaluate auricular acupuncture for acute anxiety
- 2Rigorous methodology with placebo group
- 3Rapid effect (30 minutes)
- 4Simple and inexpensive technique
Limitations
- 1Small and unequal sample across groups
- 2Tested only in healthy volunteers
- 3Did not assess actual preoperative anxiety
- 4Lack of correlation with physiological measures
Expert Commentary
Prof. Dr. Hong Jin Pai
PhD in Sciences, University of São Paulo
▸ Clinical Relevance
Perioperative anxiety is a real and underestimated clinical problem — up to 80% of adult patients arrive at the operating room with intense levels of anxiety, and the available pharmacological options carry risks of residual sedation, respiratory depression, and prolonged anesthetic recovery. This work, conducted by Yale researchers and published in a benchmark anesthesiology journal, positions auriculotherapy as a concrete alternative in this scenario. The anxiolytic effect documented as early as 30 minutes after application places the technique within a temporal window compatible with the preoperative routine. Elderly patients, those with respiratory conditions, or with contraindications to benzodiazepines represent the population that benefits most from an effective non-pharmacological approach. Integrating auriculotherapy into the pre-anesthetic preparation protocol — alongside or in place of conventional premedication — is a therapeutic hypothesis that this study supports with objective data.
▸ Notable Findings
The most striking finding is not simply the anxiolytic efficacy, but the demonstrated point specificity. The Relaxation point outperformed Shenmen — the master point of relaxation in classical Chinese doctrine, widely used in stress protocols — with a statistically robust difference between the three groups, F(2,51)=8.8, P<0.001. This suggests that auriculotherapy does not work by a nonspecific needling effect: there is a functional hierarchy among points, and careful point selection clinically matters. The persistence of the effect for 24 hours with significant difference (P<0.035) and still detectable at 48 hours, while pressure needles remained in situ, opens an interesting therapeutic dimension for managing postoperative anxiety — a period in which the pharmacological arsenal also faces constraints. The absence of response in physiological parameters in healthy volunteers was expected and does not weaken the subjective finding.
▸ From My Experience
In my practice at the HC-FMUSP Pain Center, we have incorporated auriculotherapy for many years not only for pain, but as a modulator of the anxious component that invariably accompanies patients with chronic painful conditions. What this article describes — response in 30 minutes, sustained effect — is consistent with what we routinely observe. I usually see noticeable relief of the anxious component as early as the first or second session, and the usual maintenance protocol is around eight to twelve sessions for cases of anxiety associated with chronic pain. I frequently use the Relaxation point described by the French, combined with Shenmen and systemic points according to the patient's pattern — and the association with conscious breathing techniques enhances the result. The profile that responds best is patients with situational or reactive anxiety, such as pre-procedure anxiety, distinct from severe generalized forms that require concomitant psychiatric approach. For minimally invasive ambulatory procedures, offering auriculotherapy 40 minutes beforehand is a routine I recommend to colleagues without hesitation.
Indexed scientific article
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Scientific Review

Marcus Yu Bin Pai, MD, PhD
CRM-SP: 158074 | RQE: 65523 · 65524 · 655241
PhD in Health Sciences, University of São Paulo. Board-certified in Pain Medicine, Physical Medicine and Rehabilitation, and Medical Acupuncture. Scientific review and curation of every entry in this library.
Learn more about the author →Medical disclaimer: This content is for educational purposes only and does not replace consultation, diagnosis, or treatment by a qualified professional. Some information may be assisted by artificial intelligence and is subject to inaccuracies. Always consult a physician.
Content reviewed by the medical team at CEIMEC — Integrated Centre for Chinese Medicine Studies, a reference in Medical Acupuncture for over 30 years.
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